Immune reconstitution syndrome from nontuberculous mycobacterial infection after initiation of antiretroviral therapy in children with HIV infection.
نویسندگان
چکیده
The immune reconstitution syndrome caused by nontuberculous mycobacterial (NTM) infection is reported in 9 of 153 HIV-infected children 2 to 26 weeks after initiation of antiretroviral therapy. The clinical syndrome included fever and dyspnea (2 children), fever and abdominal pain (3), subcutaneous nodules or suppurative lymphadenitis (4). The causative species were Mycobacterium avium (4), Mycobacterium scrofulaceum (3), Mycobacterium kansasii (1) and Mycobacterium simiae (1).
منابع مشابه
Mycobacterial cervicofacial lymphadenitis in human immunodeficiency virus-infected individuals after antiretroviral therapy initiation.
OBJECTIVES/HYPOTHESIS Mycobacterial infections are the leading cause of morbidity and mortality among human immunodeficiency virus (HIV)-infected individuals worldwide. Cervical lymph nodes are the most frequently affected extrapulmonary sites. Despite the substantial reduction in complications of HIV-tuberculosis coinfection, a proportion of individuals develop immune reconstitution inflammato...
متن کاملNontuberculous mycobacterial immune reconstitution syndrome in HIV-infected patients: spectrum of disease and long-term follow-up.
BACKGROUND The long-term outcome and spectrum of disease of nontuberculous mycobacterial immune reconstitution syndrome have not been described. METHODS We report the findings of an observational study. RESULTS Among 51 patients (43 with Mycobacterium avium complex [MAC] infection, 2 with Mycobacterium genavense infection, and 6 whose samples were smear positive but culture negative) from 1...
متن کاملPulmonary Mycobacterium parascrofulaceum infection as an immune reconstitution inflammatory syndrome in an AIDS patient.
Nontuberculous mycobacterial (NTM) infection in HIV (human immunodeficiency virus)-infected patients who have started highly active antiretroviral therapy (HAART) is well known to be one scenario of immune reconstitution inflammatory syndrome (IRIS). We encountered the first case in Japan of an HIV-infected patient with pulmonary Mycobacterium parascrofulaceum infection as IRIS. A 34 year-old m...
متن کاملNeck Masses as a Manifestation of Mycobacterial Immune Reconstitution Inflammatory Syndrome in Human Immunodeficiency Virus-infected Children
We described immune reconstitution infl ammatory syndrome (IRIS) associated with mycobacterial infection in 2 HIV-infected male children. Both cases had severe immune suppression at the initiation of antiretroviral therapy (ART), with a known risk of IRIS. They presented with neck masses that were enlarged and infl amed lymph nodes, which represented an enhanced immune response after 6 weeks of...
متن کاملImmune reconstitution syndrome due to bacillus Calmette-Guérin after initiation of antiretroviral therapy in children with HIV infection.
The immune reconstitution syndrome caused by bacillus Calmette-Guerin (BCG) was found in 4 HIV-infected children who were immunized with BCG at birth. The localized, suppurative, BCG-related complications developed within 10 weeks after initiation of antiretroviral therapy. The incidence rate was 2.7 cases per 100 persons (95% confidence interval, 0.7-6.7). Patients responded well to treatment ...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید
ثبت ناماگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید
ورودعنوان ژورنال:
- The Pediatric infectious disease journal
دوره 25 7 شماره
صفحات -
تاریخ انتشار 2006